Biochemistry, Genetics and Molecul: Недавние поступления
Отображаемые элементы 101-120 из 139
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Isolation and In Silico SARS-CoV-2 Main Protease Inhibition Potential of Jusan Coumarin, a New Dicoumarin from Artemisia glauca
(Molecules, 2022-03)A new dicoumarin, jusan coumarin, (1), has been isolated from Artemisia glauca aerial parts. The chemical structure of jusan coumarin was estimated, by 1D, 2D NMR as well as HR-Ms spectroscopic methods, to be 7-hydroxy-6-methoxy-3-[(2-oxo-2H-chromen-6-yl)oxy]-2H-chromen-2- one. As the first time to be introduced in nature, its potential against SARS-CoV-2 has been estimated using ...2024-09-12 -
Реконструкция структуры генофонда казахов по данным об их родорасселении
(Вавиловский журнал генетики и селекции, 2018)Использование для изучения генофонда квазигенетических маркеров – признаков небиологической природы (фамилия, род), но четко наследующихся в поколениях, – одно из направлений в популяционной генетике человека. Если для популяций Западной Европы, европейской части России и Кавказа в роли квазигенетических маркеров выступают фамилии, то для популяций Центральной Азии ...2024-09-12 -
A chirality-dependent action of vitamin C in suppressing Kirsten rat sarcoma mutant tumor growth by the oxidative combination: Rationale for cancer therapeutics
(International Journal of Cancer, 2019)Conceived and designed experiments: Sarbassov DD; Performed the cell culture and mouse studies: Wu X; Supported the xenograft study: Park M, Song MS; Optimized the drug injections: Sarbassova DA; Wrote the manuscript: Sarbassova DD, Song MS, Sarbassova DA; Supported the pancreatic cancer cell study: Ying H; Supported the colorectal cancer cell study: Bhattacharya R, Ellis ...2024-09-11 -
Interdisciplinary Research to Advance Digital Imagery and Natural Compounds for Eco-Cleaning and for Preserving Textile Cultural Heritage
(Sensors, 2022)The old fibers that make up heritage textiles displayed in museums are degraded by the aging process, environmental conditions (microclimates, particulate matter, pollutants, sunlight) and the action of microorganisms. In order to counteract these processes and keep the textile exhibits in good condition for as long as possible, both reactive and preventive interventions on ...2024-09-11 -
Innovative Technologies for Producing Foam Concrete Products Using Solar Energy
(International Journal of Engineering & Technology, 2018)An energy efficient technology and a method for the production of foam concrete products have been developed. They involve the use of solar energy in the process in order to reduce energy consumption for heat treatment, which allows to produce high-quality products with a low production cost with a daily production cycle. The technical and economic evaluation of the developed ...2024-09-11 -
Health Impact of Drying Aral Sea: One Health and Socio-Economical Approach
(Water, 2021)Once one of the largest saline lakes, the Aral Sea, was recognized as a significant environmental disaster as the water level decreased dramatically. Water level decrease increases water salinity, affecting biodiversity. Exposed lake beds become the source for fine dust picked up by the dust storms and spread across a long distance, affecting people’s health in surrounding ...2024-09-11 -
Genomic Analysis of 18th-Century Kazakh Individuals and Their Oral Microbiome
(Biology, 2021)The Asian Central Steppe, consisting of current-day Kazakhstan and Russia, has acted as a highway for major migrations throughout history. Therefore, describing the genetic composition of past populations in Central Asia holds value to understanding human mobility in this pivotal region. In this study, we analyse paleogenomic data generated from five humans from Kuygenzhar, ...2024-09-11 -
Genome sequence and assembly of the amylolytic Bacillus licheniformis T5 strain isolated from Kazakhstan soil
(BMC Genomic Data, 2024)Objectives The data presented in this study were collected with the aim of obtaining the complete genomes of specifc strains of Bacillus bacteria, namely, Bacillus licheniformis T5. This strain was chosen based on its enzymatic activities, particularly amylolytic activity. In this study, nanopore sequencing technology was employed to obtain the genome sequences of this strain. ...2024-09-11 -
Genetic polymorphism of Y-chromosome in Kazakh populations from Southern Kazakhstan
(BMC Genomics, 2023)Background The Kazakhs are one of the biggest Turkic-speaking ethnic groups, controlling vast swaths of land from the Altai to the Caspian Sea. In terms of area, Kazakhstan is ranked ninth in the world. Northern, Eastern, and Western Kazakhstan have already been studied in relation to genetic polymorphism 27 Y-STR. However, current information on the genetic polymorphism ...2024-09-11 -
Genetic polymorphism of 27 Y-STR loci in Kazakh populations from Eastern Kazakhstan
(ANNALS OF HUMAN BIOLOGY, 2023)Background: The establishment of a national haplotype database is important for forensic and genetic applications and requires studying genetic polymorphisms at Y-STR sites. However, the genetic structure of the Eastern Kazakhstan population is poorly characterised. Aim: To investigate the genetic polymorphisms of 27 Y-STR loci in the Kazakh population from Eastern Kazakhstan ...2024-09-11 -
From Biological Source to Energy Harvesting Device: Surface Protective Ionic Liquid Coatings for Electrical Performance Enhancement of Wood-Based Electronics
(Molecules, 2023)This study explores task-specific ionic liquids (TSILs) in smart floor systems, highlighting their strong electrical rectification abilities and previously established wood preservative properties. Two types of TSILs, featuring a “sweet” anion and a terpene-based cation, were used to treat selected wood samples, allowing for a comparison of their physical and electrical ...2024-09-11 -
Fe2O3 Nanoparticles Doped with Gd: Phase Transformations as a Result of Thermal Annealing
(Molecules, 2021)The aim of this work is to study the effect of the phase composition of the synthesized Fe2O3 - Gd2O3 nanoparticles on the efficiency of using magnetic hyperthermia as a basis for experiments. This class of structures is one of the most promising materials for biomedical applications and magnetic resonance imaging. In the course of the study, the dynamics of phase transformations ...2024-09-11 -
Ethanol production from cassava peels using Saccharomyces cerevisiae via ethanologenic fermentation process
(Arab Gulf Journal of Scientific Research, 2023-11)Purpose – This study aims to assess the effect of water variation on bioethanol production from cassava peels (CP) using Saccharomyces cerevisiae yeast as the ethanologenic agent. Design/methodology/approach – The milled CP was divided into three treatment groups in a small-scale flask experiment where each 20 g CP was subjected to two-stage hydrolysis. Different amount of ...2024-09-11 -
Estimating the impact of the Mongol expansion upon the gene pool of Tuvans
(Вавиловский журнал генетики и селекции, 2018)With a view to trace the Mongol expansion in Tuvinian gene pool we studied two largest Tuvinian clans – those in which, according to data of humanities, one could expect the highest Central Asian ancestry, connected with the Mongol expansion. Thus, the results of Central Asian ancestry in these two clans component may be used as upper limit of the Mongol influence ...2024-09-11 -
Environmental DNA reveals the ecology and seasonal migration of a rare sturgeon species in the Ural River
(Environmental DNA, 2023-08)Environmental DNA (eDNA) technology is an essential tool for monitoring living organisms in ecological research. The combination of eDNA methods with traditional methods of ecological observation can significantly improve the study of the ecology of rare species. Here, we present the development and application of an eDNA approach to identify rare sturgeons in the lower reaches ...2024-09-11 -
Development of an Artificial Vision for a Parallel Manipulator Using Machine‑to‑Machine Technologies
(Sensors, 2024)This research focuses on developing an artificial vision system for a flexible delta robot ma‑ nipulator and integrating it with machine‑to‑machine (M2M) communication to optimize real‑time device interaction. This integration aims to increase the speed of the robotic system and improve its overall performance. The proposed combination of an artificial vision system with M2M ...2024-09-11 -
Continuous Sign Language Recognition and Its Translation into Intonation-Colored Speech
(Sensors, 2023)This article is devoted to solving the problem of converting sign language into a consistent text with intonation markup for subsequent voice synthesis of sign phrases by speech with intonation. The paper proposes an improved method of continuous recognition of sign language, the results of which are transmitted to a natural language processor based on analyzers of morphology, ...2024-09-11 -
Comparative Analysis of Natural and Synthetic Zeolite Filter Performance in the Purification of Groundwater
(Water, 2023)Zeolite materials are among the relatively cheap and readily available materials for wastewater treatment. However, the performance of zeolite-based systems can be highly affected by the material properties. In this study, the treatment system based on natural zeolite materials from Chankanai mines in Kazakhstan was compared with a synthetic zeolite treatment system for ...2024-09-11 -
Chargaff’s second parity rule lies at the origin of additive genetic interactions in quantitative traits to make omnigenic selection possible
(PeerJ, 2023)Background. Francis Crick’s central dogma provides a residue-by-residue mechanistic explanation of the flow of genetic information in living systems. However, this principle may not be sufficient for explaining how random mutations cause continuous variation of quantitative highly polygenic complex traits. Chargaff’s second parity rule (CSPR), also referred to as intrastrand ...2024-09-11 -
Alkaloid-Based Isoxazolylureas: Synthesis and Effect in Combination with Anticancer Drugs on C6 Rat Glioma Model Cells
(Molecules, 2024)Alkaloid-based urea derivatives were produced with high yield through the reaction of anabasine and cytisine with isoxazolylphenylcarbamates in boiling benzene. Their antitumor activity, in combination with the commonly used five anticancer drugs, namely cyclophosphane, fluorouracil, etoposide, cisplatin, ribomustine with different mechanisms of action, was investigated. Based ...2024-09-11
