• miR‑19 in blood plasma reflects lung cancer occurrence but is not specifically associated with radon exposure 

      BULGAKOVA, OLGA; ZHABAYEVA, DINARA; KUSSAINOVA, ASSIYA; PULLIERO, ALESSANDRA; IZZOTTI, ALBERTO; BERSIMBAEV, RAKHMETKAZHI (ONCOLOGY LETTERS, 2018)
      Radon is one of the most powerful carcinogens, particularly in terms of lung cancer onset and development. miRNAs may be considered not only as markers of the ongoing tumorigenesis but also as a hallmark of exposure to radiation, including radon and its progeny. Therefore, the purpose of the present study was to estimate the value of plasma miR-19b-3p level as the ...
      2024-09-12
    • Innovative Technologies for Producing Foam Concrete Products Using Solar Energy 

      Aruova, Lyazat; Dauzhanov, Nabi; Tokmyrza, Batyrkhan; Utkelbaeva, Aizhan; Shashpan, Zolaman (International Journal of Engineering & Technology, 2018)
      An energy efficient technology and a method for the production of foam concrete products have been developed. They involve the use of solar energy in the process in order to reduce energy consumption for heat treatment, which allows to produce high-quality products with a low production cost with a daily production cycle. The technical and economic evaluation of the developed ...
      2024-09-11
    • Реконструкция структуры генофонда казахов по данным об их родорасселении 

      Жабагин, М.К.; Балановский, О.П.; Сабитов, Ж.М.; Темиргалиев, А.З.; Агджоян, А.Т.; Кошель, С.М.; Раманкулов, Е.М. ; Балановская, Е.В. (Вавиловский журнал генетики и селекции, 2018)
      Использование для изучения генофонда квазигенетических маркеров – признаков небиологической природы (фамилия, род), но четко наследующихся в поколениях, – одно из направлений в популяционной генетике человека. Если для популяций Западной Европы, европейской части России и Кавказа в роли квазигенетических маркеров выступают фамилии, то для популяций Центральной Азии ...
      2024-09-12
    • Estimating the impact of the Mongol expansion upon the gene pool of Tuvans 

      Damba, L.D.; Balanovskaya, Е.V.; Zhabagin, М.K.; Yusupov, Y.М.; Bogunov, Y.V.; Sabitov, Z.M. ; Agdzhoyan, А.Т.; Korotkova, N.А.; Lavryashina, М.B.; Mongush, B.B.; Kavai-ool, U.N.; Balanovsky, O.P. (Вавиловский журнал генетики и селекции, 2018)
      With a view to trace the Mongol expansion in Tuvinian gene pool we studied two largest Tuvinian clans – those in which, according to data of humanities, one could expect the highest Central Asian ancestry, connected with the Mongol expansion. Thus, the results of Central Asian ancestry in these two clans component may be used as upper limit of the Mongol influence ...
      2024-09-11
    • Machine Learning for the Communication Optimization in Distributed Systems 

      Kazhmaganbetova, Zarina; Imangaliyev, Shnar; Sharipbay, Altynbek (International Journal of Engineering & Technology, 2018)
      The objective of the work that is presented in this paper was the problem of the communication optimization and detection of the issues of computing resources performance degradation [1, 2] with the usage of machine learning techniques. Computer networks transmit payload data and the meta-data from numerous sources towards vast number of destinations, especially in multi-tenant ...
      2024-09-12
    • Association of polymorphism TP53 Arg72Pro with radon-induced lung cancer in the Kazakh population 

      Bulgakova, O.; Kussainova, A.; Kakabayev, A.; Kausbekova, A.; Bersimbaev, R. (Вавиловский журнал генетики и селекции, 2019)
      Самый распространенный тип рака в структуре онкологических заболеваний – рак легкого, который представляет собой серьезную проблему не только в Республике Казахстан, но и по всему миру. Воздействие радона классифицируется как вторая причина развития онкологии легкого. По оценкам экспертов, естественный радиационный фон составляет 80 % от среднегодовой дозы облучения населения ...
      2024-09-09
    • A chirality-dependent action of vitamin C in suppressing Kirsten rat sarcoma mutant tumor growth by the oxidative combination: Rationale for cancer therapeutics 

      Wu, Xinggang; Park, Mikyung; Sarbassova, Dilara A.; Ying, Haoqiang; Lee, Min Gyu; Bhattacharya, Rajat; Ellis, Lee; Peterson, Christine B.; Hung, Mien-Chie; Lin, Hui-Kuan; Bersimbaev, Rakhmetkazhi I.; Song, Min Sup; Sarbassov, Dos D. (International Journal of Cancer, 2019)
      Conceived and designed experiments: Sarbassov DD; Performed the cell culture and mouse studies: Wu X; Supported the xenograft study: Park M, Song MS; Optimized the drug injections: Sarbassova DA; Wrote the manuscript: Sarbassova DD, Song MS, Sarbassova DA; Supported the pancreatic cancer cell study: Ying H; Supported the colorectal cancer cell study: Bhattacharya R, Ellis ...
      2024-09-11
    • Excited State Dynamics of a CsPbBr3 Nanocrystal Terminated with Binary Ligands: Sparse Density of States with Giant Spin-Orbit Coupling Suppresses Carrier Cooling 

      Forde, Aaron; Inerbaev, Talgat; Hobbie, Erik; Kilin, Dmitri (Journal of the American Chemical Society, 2019-03)
      Fully inorganic lead halide perovskite nanocrystals (NCs) are of interest for photovoltaic and light-emitting devices due to optoelectronic properties that can be tuned/optimized via halide composition, surface passivation, doping, and confinement. Compared to bulk materials, certain excited-state properties in NCs can be adjusted by electronic confinement effects such as suppressed ...
      2024-09-12
    • Technology of Multi-stage Sterilization of Raw Materials with the Production of Feed Meal of High Biological Value 

      Iskakov, Ruslan Maratbekovich; Iskakova, Assel Maratbekovna; Issenov, Sultanbek Sansyzbaevich; Beisebekova, Dinara Maratbekovna; Khaimuldinova, Altyngul Kumashevna (Journal of Pure and Applied Microbiology, 2019-03)
      The article is devoted to the study of the sterilization of waste materials and animal feed meal. It was revealed that at the last stage of waste processing of animal origin, as a result of fine grinding in the crusher, feed meal of low biological value is obtained. As a result of research, a technology of multistage sterilization of raw materials has been developed with ...
      2024-09-12
    • Evaluation of the Efficiency of Detection and Capture of Manganese in Aqueous Solutions of FeCeOx Nanocomposites Doped with Nb2O5 

      Kozlovskiy, Artem; Egizbek, Kamila; Zdorovets, Maxim V.; Ibragimova, Milana; Shumskaya, Alena; Rogachev, Alexandr A.; Ignatovich, Zhanna V.; Kadyrzhanov, Kayrat (Sensors, 2020)
      The main purpose of this work is to study the effectiveness of using FeCeOx nanocomposites doped with Nb2O5 for the purification of aqueous solutions from manganese. X-ray diffraction, energy–dispersive analysis, scanning electron microscopy, vibrational magnetic spectroscopy, and mössbauer spectroscopy were used as research methods. It is shown that an increase in the dopant ...
      2024-09-19
    • Low-Dose Radiation Exposure with 56MnO2 Powder Changes Gene Expressions in the Testes and the Prostate in Rats 

      Fujimoto, Nariaki; Amantayeva, Gaukhar; Chaizhunussova, Nailya; Shabdarbayeva, Dariya; Abishev, Zhaslan; Ruslanova, Bakhyt; Zhunussov, Yersin; Azhimkhanov, Almas; Zhumadilov, Kassym; Petukhov, Aleksey; Stepanenko, Valeriy; Hoshi, Masaharu (International Journal of Molecular Sciences, 2020)
      To investigate the biological effects of internal exposure of radioactive 56MnO2 powder, the major radioisotope dust in the soil after atomic bomb explosions, on male reproductive function, the gene expression of the testes and the prostate was examined. Ten-week-old male Wistar rats were exposed to three doses of radioactive 56MnO2 powder (41–100 mGy in whole body doses), stable ...
      2024-09-20
    • The cell cycle regulatory gene polymorphisms TP53 (rs1042522) and MDM2 (rs2279744) in lung cancer: a meta-analysis 

      Bulgakova, O.; Kussainova, A.; Bersimbaev, R. (Вавиловский журнал генетики и селекции, 2020)
      Lung cancer is one of the most common types of cancer in the world. Although the mechanism of lung cancer is still unknown, a large number of studies have found a link between gene polymorphisms and the risk of lung cancer. The tumor suppressor p53 plays a crucial role in maintaining genomic stability and tumor prevention. MDM2 is a critical regulator of the p53 protein. ...
      2024-09-10
    • Radon Biomonitoring and microRNA in Lung Cancer 

      Bersimbaev, Rakhmet; Pulliero, Alessandra; Bulgakova, Olga; Kussainova, Assiya; Aripova, Akmara; Izzotti, Alberto (International Journal of Molecular Sciences, 2020)
      Radon is the number one cause of lung cancer in non-smokers. microRNA expression in human bronchial epithelium cells is altered by radon, with particular reference to upregulation of miR-16, miR-15, miR-23, miR-19, miR-125, and downregulation of let-7, miR-194, miR-373, miR-124, miR-146, miR-369, and miR-652. These alterations alter cell cycle, oxidative stress, inflammation, ...
      2024-09-17
    • The medieval Mongolian roots of Ychromosomal lineages from South Kazakhstan 

      Zhabagin, Maxat; Sabitov, Zhaxylyk; Tarlykov, Pavel; Tazhigulova, Inkar; Junissova, Zukhra; Yerezhepov, Dauren; Akilzhanov, Rakhmetolla; Zholdybayevа, Elena; Wei, Lan-Hai; Akilzhanova, Ainur; Balanovsky, Oleg; Balanovska, Elena (BMC Genetics, 2020)
      Background: The majority of the Kazakhs from South Kazakhstan belongs to the 12 clans of the Senior Zhuz. According to traditional genealogy, nine of these clans have a common ancestor and constitute the Uissun tribe. There are three main hypotheses of the clans’ origin, namely, origin from early Wusuns, from Niru’un Mongols, or from Darligin Mongols. We genotyped 490 samples ...
      2024-09-12
    • Phase Transformations and Photocatalytic Activity of Nanostructured Y2O3/TiO2-Y2TiO5 Ceramic Such as Doped with Carbon Nanotubes 

      Kozlovskiy, Artem L.; Zhumatayeva, Inesh Z.; Mustahieva, Dina; Zdorovets, Maxim V. (Molecules, 2020)
      This work is devoted to the study of phase transition processes in nanostructured ceramics of the Y2O3/TiO2-Y2TiO5 type doped with carbon nanotubes as a result of thermal annealing, as well as to the assessment of the prospects of the effect of phase composition on photocatalytic activity. By the method of X-ray phase analysis, it was found that an increase in the annealing ...
      2024-09-12
    • Morphology and Microstructure Evolution of Gold Nanostructures in the Limited Volume Porous Matrices 

      Yakimchuk, Dzmitry V.; Bundyukova, Victoria D.; Ustarroz, Jon; Terryn, Herman; Baert, Kitty; Kozlovskiy, Artem L.; Zdorovets, Maxim V.; Khubezhov, Soslan A.; Trukhanov, Alex V.; Trukhanov, Sergei V.; Panina, Larissa V.; Arzumanyan, Grigory M.; Mamatkulov, Kahramon Z.; Tishkevich, Daria I.; Kaniukov, Egor Y.; Sivakov, Vladimir (Sensors, 2020)
      The modern development of nanotechnology requires the discovery of simple approaches that ensure the controlled formation of functional nanostructures with a predetermined morphology. One of the simplest approaches is the self-assembly of nanostructures. The widespread implementation of self-assembly is limited by the complexity of controlled processes in a large volume where, ...
      2024-09-12
    • Effective photochemical treatment of a municipal solid waste landfill leachate 

      Makhatova, Ardak; Mazhit, Birzhan; Sarbassov, Yerbol; Meiramkulova, Kulyash; Inglezakis, Vassilis J.; Poulopoulos, Stavros G. (PLOS ONE, 2020-09)
      This work aimed at studying the photochemical treatment of a landfill leachate using ultraviolet light, hydrogen peroxide, and ferrous or ferric ions, in a batch recycle photoreactor. The effect of inorganic carbon presence, pH, initial H2O2 amount (0–9990 mg L-1) as well as Fe (II) (200–600 ppm) and Fe(III) (300–700 ppm) concentrations on the total carbon removal and color ...
      2024-09-09
    • Draft Genome Sequence of a Potential Commercial Biocellulose Producer, Strain Komagataeibacter europaeus GH1 

      Nagmetova, Gulden; Berdimuratova, Kalysh; Amirgazin, Asylulan; Shevtsov, Vladislav; Ismailova, Aisulu; Ramankulov, Yerlan; Shevtsov, Alexandr; Kurmanbayev, Askar (Microbiology Resource Announcements, 2020-10)
      In this work, we present the draft genome sequence of Komagataeibacter europaeus strain GH1, which is an extremely efficient biocellulose producer.
      2024-09-12
    • Internal doses in experimental mice and rats following exposure to neutron‑activated 56MnO2 powder: results of an international, multicenter study 

      Stepanenko, Valeriy ; Kaprin, Andrey ;  Ivanov, Sergey; Shegay, Peter ; Zhumadilov, Kassym ; Petukhov, Aleksey ; Kolyzhenkov, Timofey ; Bogacheva, Viktoria ; Zharova, Elena ;  Iaskova, Elena; Chaizhunusova, Nailya ; Shabdarbayeva, Dariya ; Amantayeva, Gaukhar ; Baurzhan, Arailym ; Ruslanova, Bakhyt ; Abishev, Zhaslan ; Apbassova, Madina ; Kairkhanova, Ynkar ; Uzbekov, Darkhan ; Khismetova, Zaituna ; Zhunussov, Yersin ; Fujimoto, Nariaki ; Sato, Hitoshi ; Shichijo, Kazuko ; Nakashima, Masahiro ; Sakaguchi, Aya ; Toyoda, Shin ; Kawano, Noriyuki ; Ohtaki, Megu ; Otani, Keiko ; Endo, Satoru ; Yamamoto, Masayoshi ; Hoshi, Masaharu  (Radiation and Environmental Biophysics, 2020-11)
      The experiment was performed in support of a Japanese initiative to investigate the biological efects of irradiation from residual neutron-activated radioactivity that resulted from the A-bombing. Radionuclide 56Mn (T1/2=2.58 h) is one of the main neutron-activated emitters during the frst hours after neutron activation of soil dust particles. In our previous studies (2016–2017) ...
      2024-09-18
    • The fabrication of the complex bio-fertilizer for wheat cultivation based on collection bacteria of the PGPR group 

      AIPOVA, RAKHILYA; ABDYKADYROVA, AIZHAN; SILAYEV, DMITRY; TAZABEKOVA, ERKIN; OSHERGINA, IRINA; TEN, EVGENIY; KURMANBAYEV, ASKAR (BIODIVERSITAS, 2020-11)
      Aipova R, Abdykadyrova A, Silayev D, Tazabekova E, Oshergina I, Ten E, Kurmanbaye A. 2020. The fabrication of the complex bio-fertilizer for wheat cultivation based on collection bacteria of the PGPR group. Biodiversitas 21: 5032-5039. The development of new types of biological products based on microbial complexes from local bacterial strains is a great theoretical and ...
      2024-09-12