Посмотр Multidisciplinary по дате публикации
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Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori
(PLOS ONE, 2018)Apurinic/apyrimidinic (AP) endonucleases play critical roles in the repair of abasic sites and strand breaks in DNA. Complete genome sequences of Helicobacter pylori reveal that this bacterial specie has a single AP endonuclease. An H. pylori homolog of Xth (HpXth) is a member of exonuclease III family, which is represented by Escherichia coli Xth. Currently, it remains unknown ...2024-10-18 -
A novel calix[4]pyrrole derivative as a potential anticancer agent that forms genotoxic adducts with DNA
(Scientific Reports, 2018)meso-(p-acetamidophenyl)-calix[4]pyrrole 3 was found to exhibit remarkable cytotoxicity towards A549 cancer cells. A comparative study including the isomer of 3meso-(m-acetamidophenyl)-calix[4]pyrrole 5, as well as molecules containing ‘fragments’ of these structures, demonstrated that both the calix[4]pyrrole and the acetamidophenyl units are essential for high cytotoxicity. ...2024-10-18 -
Recrystallization as the governing mechanism of ion track formation
(Scientific Reports, 2019)Response of dielectric crystals: MgO, Al2O3 and Y3Al5O12 (YAG) to irradiation with 167MeV Xe ions decelerating in the electronic stopping regime is studied. Comprehensive simulations demonstrated that despite similar ion energy losses and the initial excitation kinetics of the electronic systems and lattices, signifcant diferences occur among fnal structures of ion tracks ...2024-10-18 -
Investigation of phase transformations and corrosion resistance in Co/CoCo2O4 nanowires and their potential use as a basis for lithium-ion batteries
(Scientific Reports, 2019)The paper is devoted to the study of the efect of thermal annealing on the change in the structural properties and phase composition of metal Co nanostructures, as well as the prospects of their use as anode materials for lithium-ion batteries. During the study, a four-stage phase transition in the structure of nanowires consisting of successive transformations of the ...2024-10-18 -
OXYGEN EVOLUTION REACTION ON A N-DOPED CO0.5-TERMINATED CO3O4 (001) SURFACE
(PROCEEDINGS OF THE LATVIAN ACADEMY OF SCIENCES. Section B, 2020)Recent experimental findings suggest that the catalytic activity of Co3O4 for oxygen evolution reaction (OER) could be improved by nitrogen doping. We present preliminary OER modelling on a N-doped Co3O4 surface, with varying concentration of the dopant and its spatial distribution around Cooct and Cotet adsorption sites. The overpotential was calculated for two adsorption ...2024-10-18 -
The Concept of Building a Network of Digital Twins to Increase the Efficiency of Complex Telecommunication Systems
(Hindawi, 2020)+e technical literature actively discusses ideas for creating digital twins to solve a wide range of problems that arise for enterprises of various kinds. Advances in the areas of information technology and the development of the necessary software really make it possible to obtain important new results through the creation of digital twins. +is paper proposes the concept of ...2024-10-18 -
Insight into DNA substrate specifcity of PARP1-catalysed DNA poly(ADP-ribosyl)ation
(Scientific Reports, 2020)DNA-dependent poly(ADP-ribose) polymerases (PARPs) PARP1, PARP2 and PARP3 act as DNA break sensors signalling DNA damage. Upon detecting DNA damage, these PARPs use nicotine adenine dinucleotide as a substrate to synthesise a monomer or polymer of ADP-ribose (MAR or PAR, respectively) covalently attached to the acceptor residue of target proteins. Recently, it was demonstrated ...2024-10-18 -
Whole genome sequence data of Mycobacterium tuberculosis XDR strain, isolated from patient in Kazakhstan
(Data in Brief, 2020)Drug-resistant tuberculosis (TB) is a major public health problem. Clinical Mycobacterium tuberculosis (MTB) isolate with Extensively drug-resistant tuberculosis (MTB-XDR) profile was subjected to whole-genome sequencing using a nextgeneration sequencing platform (NGS) Roche 454 GS FLX+ followed by bioinformatics sequence analysis. Quality of read was checked by FastQC, ...2024-10-18 -
Effective photochemical treatment of a municipal solid waste landfill leachate
(PLOS ONE, 2020-09)This work aimed at studying the photochemical treatment of a landfill leachate using ultraviolet light, hydrogen peroxide, and ferrous or ferric ions, in a batch recycle photoreactor. The effect of inorganic carbon presence, pH, initial H2O2 amount (0–9990 mg L-1) as well as Fe (II) (200–600 ppm) and Fe(III) (300–700 ppm) concentrations on the total carbon removal and color ...2024-10-18 -
Efects of pyrolysis temperature, feedstock type and compaction on water retention of biochar amended soil
(Scientific Reports, 2021)Recent studies on water retention behaviour of biochar amended soil rarely considers the efect of pyrolysis temperature and also feedstock type into account. It is well known that pyrolysis temperature and feedstock type infuences the physical and chemical properties of biochar due to stagewise decomposition of structure and chemical bonds. Further, soil density, which is ...2024-10-18 -
The origins and spread of domestic horses from the Western Eurasian steppes
(Nature, 2021)Domestication of horses fundamentally transformed long-range mobility and warfare1 . However, modern domesticated breeds do not descend from the earliest domestic horse lineage associated with archaeological evidence of bridling, milking and corralling2–4 at Botai, Central Asia around 3500 bc3 . Other longstanding candidate regions for horse domestication, such as ...2024-10-18 -
Constitutive expression of Camelus bactrianus prochymosin B in Pichia pastoris
(Heliyon, 2021)Camel chymosin can be efficiently employed to produce cheese. Traditionally the rennet enzyme produced by the glands of the fourth stomach of ruminant animals (abomassum) is used in cheese making. Full-length Camelus bactrianus (Bactrian camel) prochymosin gene was synthesized and constitutively expressed in Pichia pastoris cells under glyceraldehydes-3-phosphate dehydrogenase ...2024-10-18 -
Biological impacts on the lungs in rats internally exposed to radioactive 56MnO2 particle
(Scientific Reports, 2021)To understand the radiation efects of the atomic bombing of Hiroshima and Nagasaki among the survivors, radiation from neutron-induced radioisotopes in soil should be considered in addition to the initial radiation directly received from the bombs. 56Mn, which emits both β particles and γ-rays, is one of the dominant radioisotopes created in soil by neutrons from the bomb. ...2024-10-18 -
Improved thermoelectric performance of Bideficient BiCuSeO material doped with Nb, Y, and P
(iScience, 2021-10)Thermoelectric materials convert waste heat into electric energy. Oxyselenidebased material, specifically, p-type BiCuSeO, is one of the most promising materials for these applications. There are numerous approaches to improve the heatto-electricity conversion performance. Usually, these approaches are applied individually, starting from the pure intrinsic material. Higher ...2024-10-18 -
A study of transformer‑based end‑to‑end speech recognition system for Kazakh language
(Scientific Reports, 2022)Today, the Transformer model, which allows parallelization and also has its own internal attention, has been widely used in the feld of speech recognition. The great advantage of this architecture is the fast learning speed, and the lack of sequential operation, as with recurrent neural networks. In this work, Transformer models and an end-to-end model based on connectionist ...2024-10-18 -
Efect of thickness and reaction media on properties of ZnO thin flms by SILAR
(Scientifc Reports, 2022)Zinc oxide (ZnO) is one of the most promising metal oxide semiconductor materials, particularly for optical and gas sensing applications. The infuence of thickness and solvent on various features of ZnO thin flms deposited at ambient temperature and barometric pressure by the sequential ionic layer adsorption and reaction method (SILAR) was carefully studied in this work. ...2024-10-18 -
Immune System Response after Immobilization Stress in the Background of Ionizing Radiation
(TRENDS IN SCIENCES, 2022)We studied the combined effect of gamma radiation (6 Gy, remote period) and immobilization stress on immunological reactivity. Materials and methods. To address this, we carried out experiments on 40 white male Wistar rats weighing 220 ± 20 g, which were divided into 4 groups: Group I - intact animals, group II - animals exposed to gamma radiation (dose of 6 Gy), group III ...2024-10-18 -
Treatment of waste stabilization pond effluent using natural zeolite for irrigation potential
(PLOS ONE, 2022)Direct utilization of treated effluent from natural treatment systems for irrigation can be challenging on sensitive plants due to high levels of salinity. Post-treatment of such an effluent prior to its applicability in irrigation can be of significant importance. In this study, the wastewater from a natural treatment plant was treated using a lab-scale filtration system with ...2024-10-18 -
Cloning, expression, and characterization of a recombinant xylanase from Bacillus sonorensis T6
(PLOS ONE, 2022-03)Xylanase is one of industrial enzymes with diverse applications including the paper-bleaching industry and feed additives. Here, a strain having xylanolytic activity and identified as Bacillus sonorensis T6 was isolated from soil. A secretory enzyme was identified by massspectrometry as a xylanase of glycosyl hydrolase family 11, with a molecular weight of 23.3 kDa. The xylanase ...2024-10-18
