Аннотации:
At present time one of the great interest is represented on the biologic activities of
quercetin a polyphenol relating to the class of flavonoids, natural products generally known for their
beneficial actions on health. With the aim of obtaining new derivatives of quercetin which would
possess a potential of showing valuable biological activity, 5-hydroxy-3,3’,4’,7-tetratosyl flavone was
synthesized by base catalyzed etherification of the starting material with 4-toluenesulfonyl chloride
(TsCl). The chemical structure of the derived molecule was established by X-ray crystallographic
analysis. The 1 H and 13 C NMR spectra of this compound were interpreted using 2D NMR spectroscopy. The new synthesized compound was tested for cytotoxic and antiradical activities and its
other possible pharmacological properties were predicted using PASS software.
