Abstract:
The Chamaenerion genus, particularly Chamaenerion angustifolium and Chamaenerion latifolium, is recognized for its rich phytochemical composition and extensive medicinal
properties. These species are abundant in polyphenols, flavonoids, and tannins, which
contribute to their potent antioxidant, antimicrobial, and anticancer activities. This review
provides a comprehensive analysis of their phytochemical constituents, with an emphasis
on how processing methods, including fermentation, influence bioactivity. Notably, fermentation enhances the levels of key bioactive compounds, such as oenothein B, gallic
acid, and ellagic acid, thereby increasing their pharmacological potential. Additionally,
this review evaluates the biological activities of Chamaenerion species in relation to their
chemical composition, while also considering the limitations of current studies, such as the
lack of in vivo or clinical trials. The literature for this review was sourced from scientific
databases, including PubMed, Scopus, and ScienceDirect, covering research from 2010 to
2024. Future studies should focus on optimizing extraction methods, elucidating synergistic
bioactivities, and conducting in-depth clinical trials to validate their efficacy and safety
